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Uncover the Nuclear Proteomic Landscape with Enriched Nuclei Followed by Label-Free Quantitative Mass Spectrometry
Bovine Canine Cell Culture GENE PCR Peptide Protein Salmonella Sheep Torpedo Trout Turkey Vertebrate Virus Xenopus Yeast

Uncover the Nuclear Proteomic Landscape with Enriched Nuclei Followed by Label-Free Quantitative Mass Spectrometry

25 min read
Handled with gentle pulse or beneath sure diurnal situations, photoreceptors can translocate into nucleus adopted by conformation change. Many vital elements of sunshine signaling pathways additionally majorly perform in nucleus. Therefore, it’s helpful to ascertain a mixed methodology to uncover and evaluate the nuclear proteomic panorama among the many mutants of sunshine signaling elements.
Right here we describe an optimized methodology to isolate nucleus with seedlings rising beneath gentle/darkish cycles for additional characterizing the nuclear proteome with label-free quantitation by liquid chromatography mass spectrometry (LC-MS).

Proteomics of Herpes Simplex Virus Sort 1 Nuclear Capsids

Herpes simplex virus replicates within the nucleus, the place new capsids are assembled. It produces procapsids devoid of nucleic acid however containing the preVP22a scaffold protein. These thermo-unstable particles then mature into A-, B- or C-nuclear icosahedral capsids, relying on their potential to shed the proteolytically processed scaffold and incorporation of the viral genome.
To review how these viral capsids differ, we carried out proteomics research of extremely enriched HSV-1 A-, B- and C-nuclear capsids, relying partially on a novel and highly effective circulate virometry method to purify C-capsids. We discovered that the viral particles contained the anticipated capsid elements and recognized a number of tegument proteins within the C-capsid fraction (pU<sub>L</sub>21, pU<sub>L</sub>36, pU<sub>L</sub>46, pU<sub>L</sub>48, pU<sub>L</sub>49, pU<sub>L</sub>50, pU<sub>L</sub>51 and pU<sub>S</sub>10).
Furthermore, quite a few ribosomal, hnRNPs and different host proteins, absent from the uninfected controls, have been detected on the capsids with a few of them seemingly particular to C-capsids (glycogen synthase, 4 completely different keratin-related proteins, fibronectin 1 and PCBP1). A subsequent proteomics evaluation was carried out to rule out the presence of protein complexes which will share related density because the viral capsids however don’t in any other case work together with them.
Utilizing pUL25 or VP5 mutant viruses incapable of assembling C-nuclear or all nuclear capsids, respectively, we confirmed the majority of our preliminary findings. Naturally, it is going to subsequent be vital to handle the purposeful relevance of those proteins.<b>IMPORTANCE</b> A lot is thought in regards to the biology of herpesviruses. This consists of their distinctive potential to traverse the 2 nuclear envelopes by sequential budding and fusion steps. For HSV-1, this means the pU<sub>L</sub>31/pU<sub>L</sub>34 and pU<sub>L</sub>17/pU<sub>L</sub>25 complexes which will favor C-capsid egress.
Uncover the Nuclear Proteomic Landscape with Enriched Nuclei Followed by Label-Free Quantitative Mass Spectrometry
Nonetheless, this choice course of just isn’t clear, nor are all of the variations that distinguish A-, B- and C-capsids. The current examine probes what proteins compose these capsids, together with host proteins. This could open up new analysis avenues to make clear the biology of this most fascinating household of viruses. It additionally reiterates using circulate virometry as an revolutionary instrument to purify viral particles.

A Novel Proteomic Methodology Reveals NLS Tagging of T-DM1 Contravenes Classical Nuclear Transport in a Mannequin of HER2-Constructive Breast Most cancers

The following breakthrough for protein therapeutics is efficient intracellular supply and accumulation inside goal cells. Nuclear localization sign (NLS)-tagged therapeutics have been hindered by the shortage of environment friendly nuclear localization because of endosome entrapment.
Though improvement of methods for tagging therapeutics with applied sciences able to elevated membrane penetration has resulted in proportional elevated efficiency, nonspecific membrane penetration limits goal specificity and, therefore, widespread medical success. There’s a long-standing concept that nuclear localization of NLS-tagged brokers happens completely by way of classical nuclear transport.
Within the current examine, we modified the antibody-drug conjugate trastuzumab-emtansine (T-DM1) with a classical NLS linked to cholic acid (cell accumulator [Accum]) that permits modified antibodies to flee endosome entrapment and enhance nuclear localization effectivity with out abrogating receptor focusing on. In parallel, we developed a proteomics-based methodology to judge nuclear transport.
Accum-modified T-DM1 considerably enhanced cytotoxic efficacy within the human epidermal development issue receptor 2 (HER2)-positive SKBR3 breast most cancers system. We found that efficacy was depending on the nonclassical importin-7.
Our analysis reveals that when a number of classical NLS tagging happens, cationic cost build-up versus sequence dominates and turns into a substrate for importin-7. This examine leads to an efficient goal cell-specific NLS therapeutic and a normal method to information future NLS-based improvement initiatives.

Affinity proteomic dissection of the human nuclear cap-binding complicated interactome

A 5′,7-methylguanosine cap is a quintessential function of RNA polymerase II-transcribed RNAs, and a textbook side of co-transcriptional RNA processing. The cap is sure by the cap-binding complicated (CBC), canonically consisting of nuclear cap-binding proteins 1 and a couple of (NCBP1/2). Curiosity within the CBC has not too long ago renewed because of its participation in RNA-fate selections by way of interactions with RNA productive components in addition to with adapters of the degradative RNA exosome.
A novel cap-binding protein, NCBP3, was not too long ago proposed to type an alternate CBC along with NCBP1, and to work together with the canonical CBC together with the protein SRRT. The theme of post-transcriptional RNA destiny, and the way it pertains to co-transcriptional ribonucleoprotein meeting, is plentiful with difficult, ambiguous, and certain incomplete fashions.

Rat Embryo PrimaCell1: Normal Embryonic Chorion Cells Growth Medium
9-25031 5 x 100 ml Ask for price

Chick Embryo Extract, Lyophilized
C1163-010 10ml
EUR 481.2

Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-82532 1 Kit Ask for price

Mouse 3T3 (NIH), embryo lysate
MCL-1282 100ug
EUR 255.6

Rat Embryo Tissue Preparation Buffer 1: Normal Embryonic Chorion Cells
9-80238 1 x 100 ml Ask for price

Rat Thymocyte Nuclear Protein 1 (THYN1) Protein
20-abx650182
  • EUR 744.00
  • EUR 326.40
  • EUR 2230.80
  • EUR 878.40
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

CLC/Ipomoea Medium, Embryo Production
CP006-010 10X1L
EUR 118.8

CLC/Ipomoea Medium, Embryo Production
CP006-500 50L
EUR 151.2

Rat Embryo PrimaCell3: Normal Fetal Epidermal Keratinocytes
2-82533 1 Kit Ask for price

Mouse Embryo PrimaCell1: Normal Embryonic Chorion Cells
2-82030 1 Kit Ask for price

Human Embryo PrimaCell1: Normal Embryonic Chorion Cells
2-96050 1 Kit Ask for price

Rat Embryo PrimaCell4: Normal Trophoblast Cells Growth Medium
9-25034 5 x 100 ml Ask for price

Mouse 3T3 (Balb), murine embryo lysate
MCL-1212 100 ug
EUR 255.6

Rat Sp100 Nuclear Antigen (Sp100) Protein
20-abx168513
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

ELISA kit for Rat Nuclear protein MDM1 (MDM1)
KTE100643-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Nuclear protein MDM1 (MDM1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear protein MDM1 (MDM1)
KTE100643-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Nuclear protein MDM1 (MDM1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear protein MDM1 (MDM1)
KTE100643-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Nuclear protein MDM1 (MDM1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Total RNA - Rat Normal Tissue: Embryo (RtRAN: 17-19 days)
R1434000-50 50 ug
EUR 209

CMV protein (nuclear)
30-AC98 1 mg
EUR 548.4
Description: Purified native CMV protein (nuclear)

Rat Nuclear Factor I/X (NFIX) Protein
20-abx650671
  • EUR 878.40
  • EUR 343.20
  • EUR 2715.60
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Nuclear Matrix Protein 66 ELISA kit
E02N0031-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Matrix Protein 66 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear Matrix Protein 66 ELISA kit
E02N0031-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Matrix Protein 66 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear Matrix Protein 66 ELISA kit
E02N0031-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Matrix Protein 66 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear matrix protein 22 ELISA kit
E02N0590-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Nuclear matrix protein 22 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear matrix protein 22 ELISA kit
E02N0590-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Nuclear matrix protein 22 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear matrix protein 22 ELISA kit
E02N0590-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Nuclear matrix protein 22 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Nuclear protein 1 Antibody
abx018122-100ug 100 ug
EUR 410.4

Rat Nuclear Factor Kappa B (NFkB) Protein
20-abx168498
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Thymocyte nuclear protein 1(THYN1) ELISA kit
E02T0692-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Thymocyte nuclear protein 1(THYN1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Thymocyte nuclear protein 1(THYN1) ELISA kit
E02T0692-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Thymocyte nuclear protein 1(THYN1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Thymocyte nuclear protein 1(THYN1) ELISA kit
E02T0692-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Thymocyte nuclear protein 1(THYN1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Embryo Tissue Preparation Buffer 4: Normal Trophoblast Cells
9-80241 1 x 100 ml Ask for price

Thymocyte Nuclear Protein 1 Protein
20-abx261394
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Rat Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts Growth Medium
9-25032 5 x 100 ml Ask for price

Nuclear Protein Extraction Kit
BSP009 50Preps
EUR 106.98

Rat Embryo FibrOut1: Fibroblast Inhibitory System (for 500 ml medium)
7-15214 1 Kit Ask for price

Rat Embryo FibrOut3: Fibroblast Inhibitory System (for 500 ml medium)
7-15215 1 Kit Ask for price

Rat Embryo FibrOut4: Fibroblast Inhibitory System (for 500 ml medium)
7-15216 1 Kit Ask for price

Rat Nuclear Respiratory Factor 1 (NRF1) Protein
20-abx654593
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Embryo PrimaCell4: Normal Trophoblast Cells
2-82033 1 Kit Ask for price

Human Embryo PrimaCell4: Normal Trophoblast Cells
2-96053 1 Kit Ask for price

Mouse Embryo OptiTDS1: Tissue Dissociation System
4-28144 1 Kit Ask for price

Mouse Embryo OptiTDS2: Tissue Dissociation System
4-28145 1 Kit Ask for price

Mouse Embryo OptiTDS3: Tissue Dissociation System
4-28146 1 Kit Ask for price

Mouse Embryo OptiTDS4: Tissue Dissociation System
4-28147 1 Kit Ask for price

Human Embryo OptiTDS1: Tissue Dissociation System
4-28050 1 Kit Ask for price

Human Embryo OptiTDS2: Tissue Dissociation System
4-28051 1 Kit Ask for price

Human Embryo OptiTDS3: Tissue Dissociation System
4-28052 1 Kit Ask for price

Human Embryo OptiTDS4: Tissue Dissociation System
4-28053 1 Kit Ask for price

Rat Embryo PrimaCell3: Normal Fetal Epidermal Keratinocytes Growth Medium
9-25033 5 x 100 ml Ask for price

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat)
4-PAC791Ra01
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1)

Mouse Embryo PrimaCell1: Normal Embryonic Chorion Cells Growth Medium
9-32030 5 x 100 ml Ask for price

Human Embryo PrimaCell1: Normal Embryonic Chorion Cells Growth Medium
9-46050 5 x 100 ml Ask for price

Rat Nuclear RNA Export Factor 1 (NXF1) Protein
20-abx168840
  • EUR 777.60
  • EUR 326.40
  • EUR 2364.00
  • EUR 927.60
  • EUR 560.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Nuclear Receptor Coactivator 3 (NCOA3) Protein
20-abx168543
  • EUR 878.40
  • EUR 343.20
  • EUR 2749.20
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nuclear Protein 1 (NUPR1) Antibody
abx430003-200ul 200 ul
EUR 343.2

Nuclear Protein 1 (NUPR1) Antibody
20-abx302286
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Embryo Tissue Preparation Buffer 2: Normal Fetal Dermal Fibroblasts
9-80239 1 x 100 ml Ask for price

Mdm1 Nuclear Protein (MDM1) Antibody
20-abx216769
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

Mdm1 Nuclear Protein (MDM1) Antibody
abx235075-100ug 100 ug
EUR 610.8

Mdm1 Nuclear Protein (MDM1) Antibody
20-abx113633
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Mdm1 Nuclear Protein (MDM1) Antibody
20-abx327975
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Mdm1 Nuclear Protein (MDM1) Antibody
abx026744-400ul 400 ul
EUR 627.6

Mdm1 Nuclear Protein (MDM1) Antibody
abx026744-80l 80 µl
EUR 343.2

Rat Nuclear transition protein 2(TNP2) ELISA kit
E02N0577-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Nuclear transition protein 2(TNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear transition protein 2(TNP2) ELISA kit
E02N0577-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Nuclear transition protein 2(TNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear transition protein 2(TNP2) ELISA kit
E02N0577-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Nuclear transition protein 2(TNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear migration protein nudC (NUDC) ELISA Kit
abx391735-96tests 96 tests
EUR 1093.2

Poly(A) Binding Protein, Nuclear 1 Protein
20-abx261243
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Rat Embryo Tissue Preparation Buffer 3: Normal Fetal Epidermal Keratinocytes
9-80240 1 x 100 ml Ask for price

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), PE
4-PAC791Ra01-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with PE.

Human Embryo Tissue Preparation Buffer 1: Normal Embryonic Chorion Cells
9-80050 1 x 100 ml Ask for price

Mouse Embryo Tissue Preparation Buffer 1: Normal Embryonic Chorion Cells
9-80144 1 x 100 ml Ask for price

Rat Hepatocyte Nuclear Factor 1 Beta (HNF1b) Protein
20-abx653732
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), APC
4-PAC791Ra01-APC
  • EUR 436.80
  • EUR 4254.00
  • EUR 1176.00
  • EUR 560.40
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with APC.

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), Cy3
4-PAC791Ra01-Cy3
  • EUR 532.80
  • EUR 5622.00
  • EUR 1518.00
  • EUR 697.20
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with Cy3.

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), HRP
4-PAC791Ra01-HRP
  • EUR 398.40
  • EUR 3706.80
  • EUR 1039.20
  • EUR 505.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with HRP.

GTP-Binding Nuclear Protein RAN (RAN) Protein
20-abx262891
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Rat Embryo PrimaCell1: Normal Embryonic Chorion Cells Growth Supplements with Serum (for 500 ml medium)
9-26031 1 Set Ask for price

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), FITC
4-PAC791Ra01-FITC
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with FITC.

Flystuff (47-102) Grape Agar For Embryo Collection
FLY1082 PK25
EUR 362.96

Rat Nuclear Receptor Interacting Protein 1 ELISA kit
E02N0045-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Receptor Interacting Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear Receptor Interacting Protein 1 ELISA kit
E02N0045-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Receptor Interacting Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear Receptor Interacting Protein 1 ELISA kit
E02N0045-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Nuclear Receptor Interacting Protein 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 2(CSRNP2) ELISA kit
E02C2113-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 2(CSRNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 2(CSRNP2) ELISA kit
E02C2113-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 2(CSRNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 2(CSRNP2) ELISA kit
E02C2113-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 2(CSRNP2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 3(CSRNP3) ELISA kit
E02C2114-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 3(CSRNP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 3(CSRNP3) ELISA kit
E02C2114-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 3(CSRNP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Cysteine/serine rich nuclear protein 3(CSRNP3) ELISA kit
E02C2114-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Cysteine/serine rich nuclear protein 3(CSRNP3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Nuclear Autoantigenic Sperm Protein (NASP) ELISA Kit
20-abx391725
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Thymocyte Nuclear Protein 1 (THYN1) Protein
20-abx650181
  • EUR 661.20
  • EUR 292.80
  • EUR 1914.00
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nuclear Protein Hcc-1 (HCC1) Antibody
abx217271-100ug 100 ug
EUR 526.8

Mouse Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-82031 1 Kit Ask for price

Human Embryo PrimaCell2: Normal Fetal Dermal Fibroblasts
2-96051 1 Kit Ask for price

ELISA kit for Rat Nuclear transition protein 2 (TNP2)
KTE100054-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Nuclear transition protein 2 (TNP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear transition protein 2 (TNP2)
KTE100054-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Nuclear transition protein 2 (TNP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear transition protein 2 (TNP2)
KTE100054-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Nuclear transition protein 2 (TNP2) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human BTG3 Associated Nuclear Protein (BANP) Protein
20-abx652714
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Nuclear Autoantigenic Sperm Protein, Histone Binding (NASP) Protein
20-abx650104
  • EUR 811.20
  • EUR 343.20
  • EUR 2498.40
  • EUR 961.20
  • EUR 577.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), Biotinylated
4-PAC791Ra01-Biotin
  • EUR 390.00
  • EUR 3189.60
  • EUR 932.40
  • EUR 480.00
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with Biotin.

Melanoma Nuclear Protein 18 (MEL18) Antibody
abx430561-200ul 200 ul
EUR 460.8

RAN Antibody / Ras-related nuclear protein
R32825 100 ug
EUR 356.15
Description: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease.

Mouse Embryo PrimaCell3: Normal Fetal Epidermal Keratinocytes
2-82032 1 Kit Ask for price

Human Embryo PrimaCell3: Normal Fetal Epidermal Keratinocytes
2-96052 1 Kit Ask for price

Smad Nuclear Interacting Protein 1 Protein
20-abx261342
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Inactivated VZV Antigen (Human Embryo Lung Cell Culture)
VAng-0650Lsx-inquire inquire Ask for price
Description: VZV (Strain Ellen), inactivated by Beta-propiolactone. 7.61 mg/mL.

Rat Nuclear Mitotic AppaRatus Protein 1(NUMA1)ELISA Kit
QY-E10566 96T
EUR 433.2

Thymocyte Nuclear Protein 1 (THYN1) Antibody
abx238682-100ug 100 ug
EUR 610.8

Thymocyte Nuclear Protein 1 (THYN1) Antibody
20-abx211306
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Thymocyte Nuclear Protein 1 (THYN1) Antibody
20-abx131638
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Thymocyte Nuclear Protein 1 (THYN1) Antibody
20-abx131639
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Thymocyte Nuclear Protein 1 (THYN1) Antibody
20-abx116090
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Thymocyte Nuclear Protein 1 (THYN1) Antibody
20-abx339588
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Rat PEST proteolytic signal-containing nuclear protein (PCNP) ELISA Kit
abx391793-96tests 96 tests
EUR 1093.2

Thymocyte Nuclear Protein 1 (THYN1) Polyclonal Antibody (Rat), APC-Cy7
4-PAC791Ra01-APC-Cy7
  • EUR 729.60
  • EUR 8364.00
  • EUR 2208.00
  • EUR 976.80
  • EUR 402.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat Thymocyte Nuclear Protein 1 (THYN1). This antibody is labeled with APC-Cy7.

Nuclear Matrix Protein p84 antibody
70R-13662 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Nuclear Matrix Protein p84 antibody

Nuclear Matrix Protein p84 Antibody
49738-100ul 100ul
EUR 399.6

Nuclear Matrix Protein p84 Antibody
49738-50ul 50ul
EUR 286.8

Nuclear Transport Factor 2 Protein
20-abx260609
  • EUR 3433.20
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 25 ug
  • 5 ug

Sp110 Nuclear Body Protein Antibody
20-abx115748
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Rat Smad nuclear-interacting protein 1 (SNIP1) ELISA Kit
abx391974-96tests 96 tests
EUR 1093.2

Mouse Nuclear protein 1, Nupr1 ELISA KIT
ELI-36782m 96 Tests
EUR 1038

Human Nuclear protein 1, NUPR1 ELISA KIT
ELI-13386h 96 Tests
EUR 988.8

BTG3 Associated Nuclear Protein (BANP) Antibody
abx230799-100ug 100 ug
EUR 610.8

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx171483
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx321572
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx006024
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx003640
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx111276
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

BTG3 Associated Nuclear Protein (BANP) Antibody
20-abx175631
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug

ELISA kit for Rat Nuclear autoantigenic sperm protein (NASP)
KTE100520-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat Nuclear autoantigenic sperm protein (NASP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear autoantigenic sperm protein (NASP)
KTE100520-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat Nuclear autoantigenic sperm protein (NASP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear autoantigenic sperm protein (NASP)
KTE100520-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat Nuclear autoantigenic sperm protein (NASP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human Nuclear protein MDM1, MDM1 ELISA KIT
ELI-20467h 96 Tests
EUR 988.8

Human Mdm1 Nuclear Protein (MDM1) ELISA Kit
abx381384-96tests 96 tests
EUR 1093.2

Mouse Nuclear protein MDM1, Mdm1 ELISA KIT
ELI-08463m 96 Tests
EUR 1038

Recombinant Human Thymocyte Nuclear Protein 1
7-06664 5µg Ask for price

Recombinant Human Thymocyte Nuclear Protein 1
7-06665 20µg Ask for price

Recombinant Human Thymocyte Nuclear Protein 1
7-06666 1mg Ask for price

Cytoplasmic and Nuclear Protein Extraction Kit
AR0106 1kit
EUR 121.2

Recombinant Thymocyte Nuclear Protein 1 (THYN1)
4-RPC791Hu01
  • EUR 464.06
  • EUR 247.20
  • EUR 1410.24
  • EUR 550.08
  • EUR 980.16
  • EUR 386.40
  • EUR 3345.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Thymocyte Nuclear Protein 1 expressed in: E.coli

Recombinant Thymocyte Nuclear Protein 1 (THYN1)
4-RPC791Ra01
  • EUR 528.58
  • EUR 265.20
  • EUR 1652.16
  • EUR 630.72
  • EUR 1141.44
  • EUR 429.60
  • EUR 3950.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Thymocyte Nuclear Protein 1 expressed in: E.coli

Rat Nuclear Receptor Interacting Protein 1 (NRIP1) ELISA Kit
abx353802-96tests 96 tests
EUR 801.6

Human GTP-binding nuclear protein Ran (RAN)
1-CSB-EP019307HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human GTP-binding nuclear protein Ran(RAN) expressed in E.coli

Chicken Nuclear protein MDM1, MDM1 ELISA KIT
ELI-22770c 96 Tests
EUR 1113.6

Anti-P34 cdc-2 Nuclear Protein antibody
STJ16100759 100 µg
EUR 487.2

Human Nuclear Matrix Protein 4 (NMP4) Protein
20-abx165940
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Nuclear Factor, Erythroid Derived 2 Like Protein 2 (NFE2L2) Protein
20-abx166221
  • EUR 878.40
  • EUR 343.20
  • EUR 2715.60
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nuclear Receptor-Interacting Protein 3 Protein
20-abx262590
  • EUR 393.60
  • EUR 7676.40
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

HSV2 antibody (nuclear regulatory protein)
10C-CR2122M4 100 ug
EUR 489.6
Description: Mouse monoclonal HSV2 antibody (nuclear regulatory protein)

Sp140 Nuclear Body Protein (SP140) Polyclonal Antibody (Human, Rat)
4-PAN896Hu01
  • EUR 313.20
  • EUR 3280.80
  • EUR 811.20
  • EUR 396.00
  • EUR 264.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Sp140 Nuclear Body Protein (SP140)

Human Sp140 Nuclear Body Protein (SP140) Protein
20-abx167879
  • EUR 878.40
  • EUR 343.20
  • EUR 2715.60
  • EUR 1045.20
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Nuclear Cap Binding Protein Subunit 2 Protein
20-abx261392
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

p100 Nuclear Coactivator Protein antibody
20R-2593 100 uL
EUR 612
Description: Guinea Pig polyclonal p100 Nuclear Coactivator Protein antibody

Recombinant Ebola-Z Nuclear Protein (aa 630-739)
VAng-Lsx0146-inquire inquire Ask for price
Description: Ebola-Z nuclear protein(aa 630-739), Recombinant from E. coli.

Recombinant Ebola-S Nuclear Protein (aa 629-728)
VAng-Lsx0147-inquire inquire Ask for price
Description: Ebola-S nuclear protein (aa 629-728), Recombinant from E. coli.

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx214680
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx214681
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx328361
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx321684
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx000929
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx127029
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx242019
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx242241
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

GTP-Binding Nuclear Protein RAN (RAN) Antibody
20-abx119043
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
In an effort to make clear the compositions of NCBP1-, 2- and 3-related macromolecular assemblies, now we have utilized an affinity capture-based interactome display the place the experimental design and information processing have been modified to quantitatively establish interactome variations between targets beneath a variety of experimental situations. This examine generated a complete view of NCBP-protein interactions within the ribonucleoprotein context and demonstrates the potential of our method to profit the interpretation of complicated organic pathways.
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